Discovery offers promising alternative to current therapies for AMD and ROP
A research team led by scientists at Beth Israel Deaconess Medical Center and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular...
View ArticleUnwanted formation of blood vessels in the brain may cause intractable...
Unwanted formation of blood vessels (angiogenesis) in the brain is likely to be the cause of intractable walking and balance difficulties for people who suffer from Parkinson's disease. This conclusion...
View ArticleNew treatment may help patients with chronic renovascular disease
A new treatment may help patients with a chronic kidney condition that can also lead to heart problems and premature death, according to a study appearing in an upcoming issue of the Journal of the...
View ArticlePathophysiological biomarkers predict PAH prognosis
Researchers have identified three biomarkers that signify an increased risk of death or requirement for lung transplantation in patients with pulmonary arterial hypertension.
View ArticleTyrogenex announces results from phase 1 study of orally-administered X-82 in...
Tyrogenex, a privately held company focused on the development of targeted therapeutics for cancer and ophthalmology, today announced data from its phase 1 open-label study of orally-administered X-82...
View ArticleMyriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV...
Myriad RBM, a wholly-owned subsidiary of Myriad Genetics, Inc., today announced that its DiscoveryMAP platform successfully identified combinations of 15 protein biomarkers associated with...
View ArticleNew therapeutic target can prevent abnormal blood vessel growth that causes...
A study by IRB Barcelona and IDIBAPS reveals a therapeutic target to prevent the development of the many abnormal blood vessels that cause gastrointestinal bleeding—the main complication in cirrhosis.
View ArticleArray BioPharma reports top-line results from binimetinib Phase 3 trial in...
Array BioPharma today reported top-line results from the ongoing Phase 3 clinical trial of binimetinib in patients with advanced NRAS-mutant melanoma, known as the NEMO trial. The study met its primary...
View ArticleStudy sheds new light on the causes of autism
Evidence of autism may be found in the composition and malfunction of the brain's blood vessels, a team of scientists has found. Their research sheds new light on the causes of autism, which previously...
View ArticleChi-Med announces initiation of Phase III sulfatinib registration trial in...
Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited, its drug R&D subsidiary, has initiated SANET-ep, a Phase III sulfatinib (HMPL-012) registration trial in China in...
View ArticleNew project aims to develop CAR-T cell immuno-oncology cellular therapy for...
The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, the University of...
View ArticleCommon painkiller diclofenac has significant anti-cancer properties
Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.
View ArticleResearchers use ASC secreted factors to create therapeutic factor concentrate...
"Critical limb ischemia" (CLI) describes an advanced stage of peripheral artery disease characterized by obstruction of the arteries and a markedly reduced blood flow to the extremities. CLI identifies...
View ArticleNew study aims to prevent chronic cardiac failure
Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading...
View ArticleUsing acidity to detect cancer
Normally, tissues demonstrate a slightly acidic intracellular pH (pHi) and slightly alkaline extracellular pH (pHe). However, proliferating tissues demonstrate transient pH Gradient Reversal i.e....
View ArticleRomosozumab for postmenopausal women with osteoporosis meets co-primary...
Amgen and UCB today announced top-line results from the Phase 3 placebo-controlled FRActure study in postmenopausal woMen with ostEoporosis (FRAME).
View ArticleNew TAU study suggests potential therapeutic pathway to keep osteosarcoma...
Osteosarcoma is a cancer that develops in the bones of children and adolescents. It is one of the most aggressive cancers, with only a 15 per cent, five-year survival rate when diagnosed in an advanced...
View ArticleUAB researchers focus on five key areas to improve care of CVD patients
According to the Centers for Disease Control and Prevention, approximately 610,000 people die of heart disease in the United States every year — that's one in every four deaths. The impact of...
View ArticleTSRI researchers find way to predict therapeutic potential of stem cells...
Scientists from the Florida campus of The Scripps Research Institute have for the first time developed a way to predict how a specific type of stem cell will act against different diseases.
View ArticleResearchers provide new mechanism for age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of visual impairment in people over 50 in developed countries. Although this condition affects up to 20% of people between the ages of 65 and...
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