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Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary...

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Combination of demineralized bone and gene therapy shows promise for treating...

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone...

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New erectile dysfunction treatment uses high-frequency acoustical waves

Statistically speaking, 50% of all men, have experienced erectile dysfunction (ED) at some time or another, and the chance of developing ED increases as you age. The medical management of ED has...

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Rice bioengineers reveal how heart valves use different strategies to handle...

As the valves in a heart stretch with each beat, their cells take in life-giving oxygen. But if the supply is cut off, aortic and mitral valves use different strategies to compensate, according to Rice...

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AMSBIO offers extensive products to study metabolic pathways in cells

AMSBIO offers an extensive range of proteins, antibodies, assays and kits covering every single target of major cellular metabolic pathways including folate metabolism, pyruvate metabolism (with and...

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Researchers develop innovative technique to examine and quantify blood...

A study published today in the Journal of Anatomy has made an important breakthrough in the examination of blood vessels in the brain giving scientists a clearer understanding of how dementia, brain...

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New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of...

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Natural compound could reduce risk of developing triple-negative breast...

More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast...

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Scientists discover cause of tumour resistance to angiogenesis inhibitors

A new study conducted by MedUni Vienna in collaboration with scientists from Hungary and Sweden has now shown for the first time that the success of specialised drugs to inhibit blood supply to tumours...

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New RNAi treatment safely blocks ocular inflammation in mice

Scientists have developed a new RNA interference therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.

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Study shows inhibition of transgelin prevents vasculogenic mimicry in breast...

An article published in Experimental Biology and Medicine identifies a new signaling pathway involved in breast cancer cell growth. The study, led by Dr. Chan-Wha Kim, from the Department of...

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Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for...

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Cancer uses immature immune cells as support system for successful...

More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.

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Scientists discover novel therapeutic target for retinal neovascularization

A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced...

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Combination of anti-angiogenic and immune-stimulating therapies can lead to...

Scientists from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy...

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Novel method using 3D-printed patches offers potential treatment for ischemia

Ischemia results when narrowed, hardened or blocked blood vessels starve tissue, often resulting in heart attack, stroke, gangrene and other serious conditions.

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Cells key to blood vessel formation can also produce tumors and enable their...

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

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Multiparity improves outcomes after stroke in female mice

Stroke is an age-related disease that disproportionately affects women. Although experimental studies have identified several hormonal and genetic factors underlying these differences, little is known...

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Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast...

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MGH researchers identify novel mechanism behind resistance to angiogenesis...

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

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