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Study provides new insight into unknown effects of factors that regulate...

A new study by researchers at the University of Eastern Finland provides novel insight into the previously unknown effects of factors regulating blood vessel formation.

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Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

As the COVID-19 pandemic progresses with little prospect of immediate relief, a recent study by Johns Hopkins University researchers published on the preprint server medRxiv* in October 2020 discusses...

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Age can affect response to adjuvant treatment among patients with resected...

Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not

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Study better reveals the function and behavior of macrophages in cancer growth

Macrophages, cells that help engulf and destroy harmful organisms in the body, tend to be characterized as the Jekyll and Hyde of the immune system.

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Advancements in research on cancer signal transduction and treatment

Cancer is driven by numerous genetic and epigenetic changes occurring at the cellular level. These changes drive normal cells to proliferate and escape processes that usually regulate their survival...

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Novel mechanism increases arterial diameter, allows increased inflow

Upon a heart infarct or stroke, rapid restoration of blood flow, and oxygen delivery to the hypoperfused regions is of eminent importance to prevent further damage to the heart or brain. Arterial...

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Two studies find age as a primary factor in melanoma treatment resistance

Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.

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Antiangiogenic drugs increase the aggressiveness of some kidney tumors

Angiogenesis is the process by which tumors create new blood vessels that will provide them the nutrients to continue growing.

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HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

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Preeclampsia-related placental gene expression may be associated with vitamin...

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

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Novel modular design approach to antibody nanocage generation

A new study shows the benefits of using computational design to create antibody nanocages that have the required orientation.

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Unique inhibitory protein may suppress the formation of cancer cells

Researchers from Tokyo Medical and Dental University (TMDU) identify a novel role for a protein, vasohibin-1, in preventing cancer cells from spreading

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Researchers uncover key regulation step that inhibits tumor growth

Most living things need oxygen to grow and thrive. Even cancerous tumors. That's why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for survival.

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Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal...

Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt...

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Regular walnut intake may help protect against negative outcomes associated...

A new animal study, published in the Journal of Clinical Biochemistry and Nutrition, suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with...

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New drug shows promise in treating pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study...

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Researchers analyze overall survival rate of prostate cancer patients treated...

Oncotarget recently published "Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment" which reported that a retrospective study...

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New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of...

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A promising strategy to improve functional capacity of damaged muscle

Muscle is the largest organ that accounts for 40% of body mass and plays an essential role in maintaining our lives.

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Scientists find new therapeutic approach to effectively treat age-related...

Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy.

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