Researchers develop new drug-free treatment to accelerate healing of chronic...
About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can...
View ArticleResearchers focus on improving biomaterials used for bone and tissue repair
Bone injuries in the face and skull-;known as craniomaxillofacial defects-;can be caused by sports injuries, vehicle accidents, or battlefield injuries.
View ArticlePotential covalent SARS-CoV-2 spike protein inhibitors
There remains a significant need for new and effective drugs that can be used to treat COVID-19.
View ArticleCancer drug can restore memory and cognitive function in mice with...
A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.
View ArticleCRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic...
Oncotarget published "Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing" which reported that the adequate functioning of this process is...
View ArticleMutation of cysteine residues in NRP1 reduces SARS-CoV-2 spike protein entry...
Researchers have been investigating altered protein conformations in variants of concern to provide further insight for future therapies against COVID-19.
View ArticleNanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack...
A heart attack kills heart muscle cells, leading to a scar that weakens the heart, often leading to eventual heart failure. The lack of muscle repair is due to the very limited ability of mammalian...
View ArticleIntussusceptive angiogenesis contributes to tumor growth in metastatic...
For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of...
View ArticleSpecial bioactive scaffolds lead to greater functional recovery from spinal...
In mice with a spinal cord injury, mixing materials including bioactive sequences formed a polymer meshwork that improved axon regrowth, angiogenesis, and neuronal cell survival.
View ArticleMacrophages located in the cardiac tissue protect the failing heart
According to the Centers for Disease Control and Prevention, heart failure affects more than 6 million Americans and is the main cause of death for one in eight patients.
View ArticleStudy provides a new target for therapeutic intervention in Parkinson's disease
In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson's disease.
View ArticleNovel protein regulator of tumor angiogenesis may be a therapeutic target for...
A novel protein regulator of tumor angiogenesis, TMEM230, was recently characterized by researchers to have a role in tumor development and vascularization, with potential as a target for anti-tumor...
View ArticleAn assessment of pH-sensitive cationic lipid nanoparticles for drug delivery
A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.
View ArticleCasting a wider net in zebrafish imaging
In this interview, News-Medical talks to Dr. Alex Lubin and Dr. Jason Otterstrom, about the use of deep learning powered automated microscopy and image analysis for in vivo Zebrafish screening.
View ArticleInhaled CBD shrinks glioblastoma’s size in an animal model
Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report.
View ArticleResearchers identify a bivalent histone-mark switch essential for angiogenesis
Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.
View ArticleHistopathologic and molecular effects in the placenta after SARS-CoV-2...
A recent study evaluated the molecular and histopathological effects in the placenta following a SARS-CoV-2 infection during pregnancy.
View ArticleUnusual partners are key to making more blood vessels
Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.
View ArticlePhenolic extract from wild blueberries may improve wound healing
Treating wounds with an extract taken from wild blueberries may improve healing, according to a new study.
View ArticlePowerhouse-pruning protein may also help make energy rapidly available for...
A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.
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